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Oregano Oil for Yeast, Proven Treatment or Not?

Updated 1/23/2021

Medically reviewed by Dr. Atmika Paudel, PhD - Written by Dan Jackowiak Nc, HHP and Dr. Vibhuti Rana, PhD


Dr. Atmika Paudel, PhD says... The information provided here about oregano oil for yeast and other fungi is medically correct.


Oregano Oil for yeast infections has been tested extensively against molds, yeast, fungi, and Candida in the scientific field. It is a proven Candida yeast, fungal and bacteria killer.

In a study done on mice injected with Candida albicans and published in the Journal of Molecular and Cellular Biochemistry, 80% of the mice that were fed oregano oil survived more than 30 days with no sign of Candida infection, while all of the mice that were fed just olive oil died within 10 days. In addition, oregano oil was found to completely inhibit the growth of C. albicans in culture.(1)

Another 2016 study examined the effects of Oregano oil, Tea Tree oil, Thyme oil and Chamomile Blue oil against 19 strains of Candida albicans. They found that Oregano oil, Tea Tree oil, and Thyme oil had antifungal activity, while Chamomile Blue oil had none.(2)

In a clinical study performed at Teikyo University Institute of Medical Mycology in Tokyo Japan in 2007, oregano oil for yeast was added to a footbath where the water was 107.6 degrees, 99.99% of the mycelial fungi were killed. Another test was run at 81 degrees with the oil added and considerable damage was done to the fungi.(3) This would be a great way to treat athlete’s foot or toenail fungus.


oregano oil

In another test done in 2003 at the Universidade de Coimbra in Portugal, oregano oil for yeast was used against 7 different clinical isolates of Candida and 3 ATCC type strains of Candida. A fungicidal effect was observed to the membranes of the Candida strains, effectively killing it.(4)

In 2002 at the Institute for Biological Research, in Belgrade, Yugoslavia, five different essential oils were tested for anti-fungal activity against 13 fungal species. The types of fungi tested were known to cause food poisoning, effect plants, animals and were also human pathogenic species. The oils presented various degrees of inhibition against all the fungi investigated. The highest and broadest activity was shown by the carvacrol content oils, while the oil of sage was the least effective. Carvacrol from oil of oregano exhibited the highest level of anti-fungal activity among the oils tested.(5)

In another study done at the Department of Biological Sciences in South Africa in 2002, the effect of nine different oils was evaluated on the growth of Aspergillus parasiticus and Fusarium moniliforme in grains. Oregano oil for yeast was found to have an anti-fungal effect.(6)

Another study was designed to examine the inhibition of mycotoxins involved the incorporation of each of seven oils into a broth and into patty cultures. The fungal mycotoxin was identified by high-pressure liquid chromatography. Clove oil was the most inhibitory to the growth of A. parasiticus and F. moniliforme, followed by cinnamon oil, oregano and mace oils. Neem and eucalyptus oil did not affect fungal growth.

Seven essential oils from seven air-dried plant species were analyzed by gas chromatography-mass spectrometry against the fungi Penicillium digitatum in Athens Greece in 2000. The radial growth, conidial germination, and production of Penicillium digitatum were inhibited completely by oregano, thyme, dictamus, and marjoram essential oils at relatively low concentrations (250-400 microg/mL). Lavender, rosemary, and sage essential oils presented less inhibitory effect on the radial growth and conidial germination of P. digitatum.(7)

The inhibitory effects of 10 selected Turkish spices were studied by Akgül A, Kivanç M. from Turkey in 2000, oregano essential oil; thymol and carvacrol towards growth of 9 food borne fungi were investigated in culture media with a pH of 3.5 and 5.5 in 1988 in Turkey. The anti-fungal effects of sodium chloride, sorbic acid and sodium benzoate and the combined use of oregano with sodium chloride were also tested under the same conditions for comparison. Of the spices tested, only oregano showed effect on all fungi. This study was published in the International Journal of Food Microbiology. (8)

There is no doubt that oil of oregano for yeast infections is a medically verified yeast and fungi killer. However, it is hot when used straight so if you cannot stand the heat I recommend that you dilute it in a little bit of coconut oil. It can also be taken in capsule form by adding the drops to a vegetarian capsule.


Dr. Vibhuti Rana, PhD says...

The article mentioned above has elaborately explained the fungicidal effects of oregano oil. Candidiasis or other fungal issues may be tackled efficiently using alternative medicine approach and it may not be always necessary to subject your body to antifungal drugs. A recent report published in Biofouling, it was seen that a mixture of carvacrol and thymol is quite effective in treating the biofilms formed by mixed species of Candida or S. epidermidis (1). This confirmed the anti-hyphal, antiadhesion, and anti-biofilm activities of carvacrol and thymol combination. In another review which discusses the activities of basil, oregano, and thyme essential oils, it is re-affirmed that the phenolic content of the essential oil governs its antifungal properties.

Carvacrol and eugenol components of Oregano oil were able to inhibit the growth of candida species in vitro as well as in vivo (2). Not only fungal, But the range of microbes which can be targeted by Oregon ooil is quite broad and includes bacteria (methicillin-resistant S. aureus, Listeria innocua, L. monocytogenes, A. baumannii, K. pneumoniae, Citrobacter freundii, S. enteritidis, S. typhimurium, E. coli, E. coli O157:H7, P. vulgaris, P. aeruginosa, P. fluorescens, Y. enterocolitica, Bacillus subtilis, B. cereus, Serratia liquefaciens, Lactobacillus carvatus, and Lactobacillus sakes), and parasites (Blastocystis hominis, Entamoeba hartmanni, and Endolimax nana). A trending study has also shown that essential oils, when encapsulated in chitosan nanoparticles, showed remarkable reduction in the minimum inhibitory concentrations of the essential oils and subsequently helped in eradicating or reducing the biofilm quite efficiently (3). Therefore, plant essential oils like oregano, basil, and many other oils provide a huge potential for developing new antimicrobial compounds and drugs.


  1. Swetha TK, Vikraman A, Nithya C, Hari Prasath N, Pandian SK. Synergistic antimicrobial combination of carvacrol and thymol impairs single and mixed-species biofilms of Candida albicans and Staphylococcus epidermidis. Biofouling. 2020 Nov;36(10):1256-1271. doi: 10.1080/08927014.2020.1869949. Epub 2021 Jan 12. PMID: 33435734. https://pubmed.ncbi.nlm.nih.gov/33435734/
  2. http://www.jmb.or.kr/submission/Journal/027/JMB027-03-02_FDOC_1.pdf
  3. https://www.sciencedirect.com/science/article/abs/pii/S0141813020348728

Medical Review by Dr. Atmika Paudel, PhD

The article above has discussed oregano essential oil and its efficacy in inhibiting fungi growth in vitro and in animal models. The article has cited literatures to give scientific evidences regarding those activities of the oregano essential oil. Overall, the facts give in the article are correct. I am adding some facts about oregano essential oil in this commentary.

Oregano, Origanum vulgare, belongs to Lamiaceae family of flowering plant. Oregano oil is essential oil extracted from the leaves of the plant. Oregano essential oil mainly consists of monoterpenoids and monoterpenes including carvacrol, β‐fenchyl alcohol, thymol, and γ‐terpinene. (1)

Geographical localization and harvest time will greatly affect the essential oil. In a study, it was found that while organic solvent and water extracts of Origanum vulgare did not have antimicrobial activities, essential oil obtained from Origanum vulgare had antimicrobial activities. (1)

In a study published in 2019, it was shown that oregano oil enhanced digestive enzyme activity, antioxidant capability, non-specific immunity and disease resistance in a fish model.(2)

There are many studies performed to test in vitro activities of oregano essential oil along with some studies in vivo in some animal models, which has been also mentioned and cited in the above article. However; there is a lack of enough clinical evidence and clinical trial studies regarding its efficacy and safety in human use.

1. Teixeira, B., Marques, A., Ramos, C., Serrano, C., Matos, O., Neng, N.R., Nogueira, J.M.F., Saraiva, J.A. and Nunes, M.L. (2013), Chemical composition and bioactivity of different oregano (Origanum vulgare) extracts and essential oil. J. Sci. Food Agric., 93: 2707-2714. doi:10.1002/jsfa.6089
2. Dietary oregano essential oil improved the immune response, activity of digestive enzymes, and intestinal microbiota of the koi carp, Cyprinus carpio. Author: R. Zhang,X.W. Wang,L.L. Liu,Y.C. Cao,H. Zhu. Aquaculture. Elsevier, 15 March 202



All these Oregano Oil for yeast products below are very high quality.

Oregano Extract is found in Microfase

Source Naturals Wellness Oil of Oregano

North American Herb & Spice Oil of Oregano

Back to Herbal Yeast Infection Remedies

Any questions or concerns about oregano oil for yeast infections please feel free to contact us or talk to your doctor.


Article References

1. Mol Cell Biochem. 2001 Dec;228(1-2):111-7. Antifungal activities of origanum oil against Candida albicans.
2. Antifungal activity of four essential oils against Candida clinical isolates. Asian Journal of Ethnopharmacology and Medicinal Foods March 2016.
3. Inouye S, Uchida K, Nishiyama Y, Hasumi Y, Yamaguchi H, Abe S. Teikyo University Institute of Medical Mycology, Tokyo, Japan; 2007
4. Salgueiro LR, et al., at the Laboratório de Farmacognosia, Faculdade de Farmácia/CEF, Universidade de Coimbra, 3000 Coimbra, Portugal. 2003
5. Sokovic M, et al. at the Department of Plant Physiology, Institute for Biological Research, Belgrade, Yugoslavia. 2002
6. J Food Prot. 2002 Apr;65(4):683-7. Spice oils for the control of co-occurring mycotoxin-producing fungi. Juglal S, Govinden R, Odhav B. at the Department of Biological Sciences, M. L. Sultan Technikon, Durham, South Africa.
7. J Agric Food Chem. 2000 Jun;48(6):2576-81. GC-MS analysis of essential oils from some Greek aromatic plants and their fungitoxicity on Penicillium digitatum. Daferera DJ, Ziogas BN, Polissiou MG. Laboratory of General Chemistry and Laboratory of Phytopathology, Agricultural University of Athens, Greece.
8. Int J Food Microbiol. 1988 May;6(3):263-8. Inhibitory effects of selected Turkish spices and oregano components on some foodborne fungi. Akgül A, Kivanç M. Ziraat Fak., TUT Böl, Erzurum, Turkey.



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