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Last updated 2/5/2019 by Dan and Dr. Taylor
Enzymes for yeast eat the cell wall of candida and other yeasts because the cell wall is composed of fiber and glycoproteins. Many times the patient will not experience any die-off reaction at all, especially when using an enzyme that contains protease, which is a huge bonus.
Lets review the basic cell and biofilm structure of yeasts.
Candida yeast has a cell wall composed of mannoprotein-1, glucan, chitin-glucan, mannoprotein-2 and plasma membrane.
A mannoprotein is a complex carbohydrate-modified protein used by yeasts to anchor the proteins to the cell wall glucans.
Glucans are a polysaccharide fiber, that are found in the cell walls of bacteria, fungi, algae, lichens and plants such as oats and barley.
Chitins are long-chain polymer of N-acetylglucosamine, which is a derivative of glucose. It is a primary component of fungal cell walls and the exoskeletons of arthropods. It is very similar to the polysaccharide cellulose - the basic fiber component of plant cell walls.
The plasma membrane is a fatty lipid and protein layer and the nucleus of the yeast cell is also made of protein.
The fatty acids oleic, linolic, palitic, and palmitolic are found throughout its structure.
Knowing that the cell wall of candida yeast is made up of proteins with carbohydrate rich fibers including a protein and lipid nucleus, a properly designed enzyme formula should contain the necessary enzymes to digest all of these parts.
Biofilms are used by pathogenic yeasts, bacteria and viruses as a way to hide from the hosts immune system. At the same time the pathogen will release spores or cells in an attempt to spread throughout the body. Upon release of the spores the immune system mounts a defense, which causes inflammation and can make you feel sick.
Yeast biofilms generally contain parts of the cell wall structure itself.
It will be composed of cellulose, which is basically a chain of polysaccharide fibers.
The biofilm will also contain polynucleotides that are made from bonded sugars and are primarily its dna and rna material.
Also present are polypeptide
proteins and carbohydrate glucan polysaccharides.
The biofilm also contains fibrinogen and fibronectin which are the same materials that the body uses to clot the blood at wound sites.
All of these materials are bound together by lignands with stickiness properties much like lectins in wheat.
The biofilm will form in the section of the picture above marked F. The biofilm is the first thing you need to get through in order to have any effect on the yeast cell itself.
So, the biofilm is made from proteins, with carbohydrate rich fibers much like the cell wall. In addition, it contains fibrinogen, fibronectin and lignands that bind the biofilm together. More on biofilms here.
For the mannoproteins in the cell, polypeptide proteins in the biofilm, and the nucleus of the yeast cell you need a protease enzyme.
The glucans and cellulose-chitin found in both the cell wall and biofilm you need cellulase and hemicellulase. Beta-glucanase is also helpful but cellulase always has beta-glucanase side activity so you're covered in that respect.
The polysaccharides found in both the cell and biofilm can be removed with amylase, invertase and glucoamylase.
The fibrinogen, fibronection and the lignands in the biofilm can be removed with serrapeptase.
For the lipids a lipase enzyme would work. Note: Most enzyme formulas won't contain this enzyme because the lipids are less than 10% of the cell structure.
In our opinion, getting through the biofilm is the most important aspect when treating yourself for candida yeast infections. If you don't get through the biofilm, you are not going to have any success getting the yeast under control.
There are many enzymes for yeast formulas on the market today but I only want to take a look at the three most popular. They are:
Candex contains cellulase, hemicellulase, amylase, invertase and glucoamylase. It does not contain any protease to eat the mannoproteins and nucleus or serrapeptase to eat the fibrinogen in the biofilm.
Because Candex does not contain a fibrinogen or protein eating enzyme and is therefore incomplete and would not be my first choice.
contains a Cellulase Thera-blend to eat the cell wall and a Protease
Thera-blend™ to eat the protein components. The amount of enzymes per dose are very
high, especially the protease, which has been said to minimize any
die-off reactions. However, this formula is incomplete, there are no
enzymes to eat the polysaccharides or fibrinogen in the biofilm.
contains cellulase and hemicelluse that eats the biofilm and cell
wall. Protease to eat the mannoproteins and nucleus and the starch
eating enzymes lysozyme, amylase, lactase, malt diastase and
glucoamylase to help with the polysaccharides in the biofilm. This is a
pretty good formula for breaking through the biofilm and eating the cell
wall of candida yeast. However, Candizyme lacks an enzyme that eats the
fibrinogen in the biofilm, so it is also incomplete.
If I was going to use any of the above three enzyme formulas, I would take it with SerraEnzyme so you have an enzyme that will eat the fibrinogen and lignands in the biofilm.
Biofase for yeast
is very similar to the four enzyme formulas below. It contains
cellulase and hemicellase to eat the glucan and chitin component in the biofilm and
yeast cell. Glucoamylase, amylase and invertase to eat the
polysaccharides in the biofilm and cell wall. Protease to eat the polypeptides of
the biofilm, mannoproteins and nucleus of the yeast cell. Biofase also includes a
serrapeptase enzyme that eats the fibrinogen of the biofilm making it a
complete yeast eating enzyme.
Serrapeptase also goes into the blood stream and cleans the blood of
dead tissue, blood clots, plaque, cysts, fibrin and other unwanted
microbes. It also helps reduce inflammation.
This study done by Loiselle M, Anderson KW at the Department of Chemical and Materials Engineering, University of Kentucky proves that these enzymes work on the biofilms that protect bad bacteria, yeast and viruses as well. There are more links to studies on the Biofase and biofilm page above.
Biofase works extremely well when combined with Microfase, which is an herbal formula containing ingredients proven to kill yeasts; and Profase, a probiotic that is designed to kill yeast and raise immune function. The enzymes eat the biofilm and the yeast cell while also exposing it to the yeast killing herbs in Microfase. Profase provides further cleansing action and the
good bacteria clean up the waste and prevents reattachment of the
candida yeast to the intestinal wall. Profase also boosts
good bacterial levels, which is more than likely the cause of the
infection to start with.
Yeast and candida have a very hard time adapting to these enzymes for yeast just like they do to bacteria. They will boost the effects of prescription medications like Diflucan because Diflucan cannot remove the biofilm. They have no risk to your health and do not cause the candida to mutate, which Diflucan has been proven to do. Diflucan can cause yeast and candida to shape shift and become a resistant strain like candida glabrata and candida krusei. Both of these yeasts are highly resistant to Diflucan and are very hard to get rid of.
Candex costs about $47.00 for 120 capsules, add SerraEnzyme for $25.00 for a total of $72.00.
Candidase runs about $39.00 for 84 capsules plus the $25.00 for SerraEnzyme equals $64.00.
Candizyme costs about $35.00 for 90 capsules plus the $25.00 for SerraEnzyme costs you $60.00.
A Biofase 90 capsule bottle is only $39.95. A bargain when you consider you don't have to buy SerraEnzyme because serrapeptase, along with all the other enzymes required to eat the cell wall and biofilm, are in the formula.
Biofase is also offered in a 180 capsule bottle for $67.95 which lowers your expense to $33.97 per 90 capsules if you choose this bottle size.
I get asked quite often if digestive enzymes would work as well as a yeast eating enzyme because they are cheaper, and generally contain the very same enzymes as an enzyme for yeast, so here's a comparison.
The label on the right is from a 120 capsule bottle of Candex. The enzyme amounts are per two capsules so lets narrow this down to one capsule.
Cellulase 32,000 cu
Hemicellulase 20,000 hcu
Amylase 2000 skb
Invertase 500 su
Glucoamylase 100 ag
Notice the large amounts of cellulase and hemicellulase. All yeast eating enzymes will contain these in large amounts because of the glucan, chitin and cellulistic plant matter in the biofilm and cell wall, (membrane), of candida yeast.
The next label is from a Doctors Best Digestive Enzyme formula and ingredients listed are per one capsule. Although this formula is heavy on protein digesting enzymes and has a broad range of sugar digesting enzymes, the glucan, chitin and cellulistic plant matter digestive enzymes are insufficient. The amounts are:
Cellulase is 3250 cu
Hemicellulase is 750 hcu
Candex has over 10 times the amount of cellulase and 26 times the amount of hemicellulase. You will find all enzymes for yeast contain these high amounts because it is required to have any success at clearing yeast infections.
In my opinion, Biofase's closest competitor is Klaire Labs Interfase so lets do an honest comparison.
Comparing the label of Interfase to Biofase we see very similar enzyme profiles with Interfase having Beta-Glucanase and Chitosanase where Biofase does not.
However, we have tested the Cellulase and Hemi-cellulase enzymes in Biofase and they do show Beta-Glucanase and Chitosanase activity.
Chitosanase digests the very same thing as Cellulase and Hemicellulase so it really is not needed. As a matter of fact, chitin and cellulose are both made from glucose monomers, or monosaccharides, but instead of a hydroxyl group, the glucose molecules in chitin have an amyl group attached that consists of carbon and nitrogen. Cellulase and Hemicellulase digest it very effectively.
We also see that each capsule is 425mgs.
If we click on the link above for Interfase we see that it currently sells for
$52.95 on Amazon for 120 - 425mg capsules, total mgs per bottle is
51000. Per capsule cost is .441 cents.
Looking at the label
for Biofase we see each capsule contains 525mgs so Biofase per capsule
is stronger than Interfase. Total milligrams per 120 capsules is 63000.
Biofase comes in both a 90 capsule bottle and a 180 capsule bottle with the 180's costing $67.95. That's .377 cents per capsule so a 120 capsule bottle, if there was such a thing, would cost $45.24. And... you are getting more milligrams and a stronger formula.
D&G Industries also offers a 10% off Loyalty program for all orders after the first if you leave a review on the store website. That makes that $45.24 per 120 capsules turn into $40.71 ;)
You may have noticed that both Biofase and Interfase are Proprietary blends and list their enzymes in milligrams verses the specific enzyme activity of other brands. Proprietary refers to a patent, or ownership. Applying this to Biofase and Interfase, it means each company owns the rights to their specific blend of enzymes, making these products different from similarly marketed systemic enzyme supplements. This is not done to hide anything but does help to prevent foreign copycats. It's also meant to hopefully make the decision of choosing a product easier by simplifying what the product is and what it is intended to do.
In all honesty, listing enzyme activity levels for any blended enzyme formula is meaningless. No one can tell you what 32,000cu of cellulase is going to do in the body, or what 80,000spu's of serrapepetase is going to do either. In single enzyme formulas it can help to determine what's a better buy. But in blended formulas, all that matters is if it works or not. Biofase is formulated to work, which is all that matters, this is what Dave has to say:
Please post this testimonial on your website.
I have been suffering with systemic candidiasis for around 7 years and anyone who has been dealing with the same problem knows it is quite different than a yeast infection and extremely hard to get rid of. For years I have been taking Candex and it has helped but it has not eliminated my candida. Two weeks ago I decided to try Biofase for yeast and I have noticed a huge difference, it is head and shoulders above Candex. I would compare Candex to a handgun and Biofase to a bazooka and believe me when combating candida you want the bazooka as this disease is extremely ruthless. From here on out I will be ordering Biofase. Thank you Dan for all your research that has gone into making this product!
There are enzyme medical studies with testimonials from real people on this webpage about Biofase, and more testimonials here and here if you care to read them. There are also testimonials on this store website along with a Star rating.
Yes. There are no known toxicity issues with any of these enzymes for yeast.
As a matter of fact, in the book, Enzymes: The Fountain of Life by K. Miehlke, R. M. Williams, D. A. Lopez; they reference studies done on rats and guinea pigs and observed no ill effects at daily doses that are equivalent to 250 capsules a day for a 134 pound person.
In another study, rats were fed the equivalent of 2500 capsules a day daily for a short period and the rats only seemed a little fatigued. Research has also looked at cell changes and mutations. They found no negative affects at all.
They have been given GRAS status by the FDA.
What are the possible side effects of enzymes for candida yeast?
In our experience, in highly toxic individuals with high levels of yeasts or bad bacteria, it is entirely possible to have a cleansing reaction.
These people may experience nausea, a “burning sensation” in the stomach, or abdominal cramping. This is because the enzymes may aggravate pre-existing problems in the GI tract, basically they are working. If this occurs, I suggest using one half of a capsule, twice daily, emptied into eight ounces of warm water, and building up from there. To avoid this problem to start with take one capsule the first three days, two capsules day four through six, and so on, until you reach the recommended daily dose.
Many people that have the stomach pains have found that if they stop taking them altogether for a couple of days, then start back up at a lower dose, they don't have anymore problems.
Many times when using enzymes for yeast, a change in diet is not needed if the yeast infection is mild. However, it makes sense to not feed the yeast when you are trying to get rid of it. Why give it something to fight back with? It just doesn't make sense does it?
Generally, I would follow the directions on the label. But it is important to take these enzymes at least one hour or more before breakfast and at bedtime. You don't want to take them with food or any supplements that contain fiber because the enzymes will digest those and not do what you want them to do.
These enzymes for yeast infections are safe for children and the recommended dose is one-half capsule, twice daily, for each 40 pounds of body weight. However, I can't speak for the other enzymes above, but I have one year olds taking one Biofase with one Profase twice a day with very good results. For ages 14 and up, adult recommendations may be followed.
It is best to take them away from food, one hour or more before breakfast and at bedtime.
Article written by Dan and edited for accuracy by Dr. Taylor
If you have any questions about these enzymes for yeast infection please feel free to contact us from the contact page of this website.
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