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DMSA is a sulfhydryl-containing substance that binds to mercury,
lead, cadmium and zinc. It is a water-soluble, non-toxic, orally
administered metal chelator that has been in use as an antidote for
heavy metal toxicity and mercury poisoning treatment since the 1950s.
Research confirms that it is effective yet safe for removing mercury and other heavy metals from the body. The convenience of oral dosing and low toxicity often make it the chelator of choice for many applications.
20% of orally administered DMSA is absorbed through the gastrointestinal tract, which is two to four times the amount of EDTA that is absorbed.
DMSA treatment for mercury poisoning results in the greatest urinary excretion of mercury, compared to other heavy metal chelators, as well as being the most effective at removing mercury from the blood, liver, brain, spleen, lungs, large intestine, skeletal muscle and bone. Mercury excretion is greatest in the first 8 to 24 hours after ingestion. In animal studies, it has been shown to be the most efficient chelator for brain mercury, removing two-thirds of the brain mercury deposits.
Dmsa causes very few side effects, the most common being intestinal discomfort, loss of appetite, throwing up or itching. It can cause deficiencies of copper; manganese, molybdenum, magnesium, and zinc if they are not replaced by supplementation so make sure you take multimineral supplment daily.
Dosage recommendations vary widely for treatment for mercury poisoning. The Physicians Desk Reference recommends 10mg per 2.2 pounds of body weight every eight hours for 5 days, then reduce the dose to twice daily for two more weeks, off for two weeks, and repeat as necessary. This is the high dose that commonly causes the intestinal distress.
Others suggest to take 100 to 250 mgs three times a day before meals for 3 days then take 10 days off. Continue this cycle for 6 months then retest with the urine challenge test. It should be taken on an empty stomach, one hour before or two hours after a meal.
It is best to be under a doctor’s supervision when taking DMSA but not required.
I suggest that on the 10 day off periods you take zeolite. By doing so you will greatly speed up the chelation process.
Article written by Dan and edited for accuracy by Dr. Taylor
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